Insights on the toxicity of selected rare earth elements in rainbow trout hepatocytes

Lymphotoxin-β-receptor poor (LTβR^-/-) and Tumor Necrosis Issue Receptor p55 poor (parafina) mice present defects in liver regeneration (LR) after partial hepatectomy (PHx) with considerably elevated mortality. LTβR and TNFRp55 belong to the core members of the TNF/TNFR superfamily. Apparently, mixed failure of LTβR and TNFRp55 signaling after PHx leads to a whole defect in LR. Right here, we first addressed the query which liver cell inhabitants crucially requires LTβR signaling for environment friendly LR.

To this finish, mice with a conditionally focused LTβR allele (LTβR^fl/fl) had been crossed to AlbuminCre and LysozymeMCre mouse traces to unravel the perform of the LTβR on hepatocytes and monocytes/macrophages/Kupffer cells, respectively. Evaluation of those mouse traces clearly reveals that LTβR is required on hepatocytes for environment friendly LR whereas no deficit in LR was present in LTβR^fl/fl × LysMCre mice.

Second, the molecular foundation for the cooperating position of LTβR and TNFRp55 signaling pathways in LR was investigated by transcriptome evaluation of etanercept handled LTβR^-/- (LTβR^-/-/ET) mice. Bioinformatic evaluation and subsequent verification by qRT-PCR recognized novel goal genes (Cyclin-L2, Fas-Binding issue 1, interferon-related developmental regulator 1, Leucyl-tRNA Synthetase 2, and galectin-4) which might be upregulated by LTβR/TNFRp55 signaling after PHx and fail to be upregulated after PHx in LTβR^-/-/ET mice.

Power liver illness is characterised by progressive hepatic fibrosis resulting in the formation of cirrhosis regardless of the etiology with no efficient therapy at the moment accessible. Liver stiffness (LS) is at the moment the very best medical predictor of this fibrosis development regardless of the etiology. LS and hepatocytes-nonparenchymal cells (NPC) interactions are two variables recognized to be essential in regulating hepatic perform throughout liver fibrosis, however little is understood concerning the interaction of those cues. Right here, we use polydimethyl siloxane (PDMS) based mostly substrates with tunable mechanical properties to review how cell-cell interplay and stiffness regulates hepatocytes perform.

Cryo Dog (Beagle) Hepatocytes, Suspension
LODBCS01	Westburg	each	EUR 390.63

Male Beagle dog HEPATOCYTES , 10 million cells
LODBFS10-EU	Westburg	each	Ask for price

Hepatocytes of male Beagle dog in monolayer, in 6 well-plate
LODBF06-EU	Westburg	each	Ask for price

Hepatocytes of male Beagle dog in monolayer, in 12 well-plate
LODBF12-EU	Westburg	each	Ask for price

Hepatocytes of male Beagle dog in monolayer, in 24 well-plate
LODBF24-EU	Westburg	each	Ask for price

Hepatocytes of male Beagle dog in monolayer, in 48 well-plate
LODBF48-EU	Westburg	each	Ask for price

Hepatocytes of male Beagle dog in monolayer, in 96 well-plate
LODBF96-EU	Westburg	each	Ask for price

Primary Rat (Fischer) Hepatocytes, Plateable
T0108	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Rat (Fischer) Hepatocytes, Suspension
T0107	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Normal Human Primary Plateable Hepatocytes
T5539	ABM	1x10^6 cells / 1.0 ml	EUR 925

Normal Human Primary Plateable Hepatocytes
T5541	ABM	1x10^6 cells / 1.0 ml	Ask for price

Normal Human Primary Suspension Hepatocytes
T5538	ABM	1x10^6 cells / 1.0 ml	Ask for price

Primary Mouse (CD-1) Hepatocytes, Plateable
T0120	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Mouse (CD-1) Hepatocytes, Suspension
T0119	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Monkey (Cynomolgus) hepatocytes, Plateable
T0112	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Mouse (C57BI/6) Hepatocytes, Plateable
T0122	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Rat (Wistar Han) Hepatocytes, Plateable
T0106	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Minipig (Gottingen) Hepatocytes, Suspension
T0113	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Monkey (Cynomolgus) Hepatocytes, Suspension
T0111	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Mouse (C57BI/6) Hepatocytes, Suspension
T0121	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Rat (Wistar Han) Hepatocytes, Suspension
T0105	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Enhanced Primary Human Hepatocytes - 5 million
T5996	ABM	5x10^6 cells / 1.0 ml	Ask for price

Primary Rat (Sprague Dawley) Hepatocytes, Plateable
T0104	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Rat (Sprague Dawley) Hepatocytes, Suspension
T0103	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Human Hepatocytes, Transporter Uptake Qualified
T0125	ABM	5x10^5 cells / 1.0 ml	EUR 3500

Enhanced Primary Human Hepatocytes – 1 Million
T5995	ABM	1x10^6 cells / 1.0ml	Ask for price

Primary Human Hepatocytes, Induction Qualified, Plateable
T0128	ABM	5x10^5 cells / 1.0 ml	EUR 2625

Primary Human Hepatocytes, Metabolism Qualified, Plateable
T0124	ABM	5x10^5 cells / 1.0 ml	EUR 2625

Primary Human Hepatocytes, Metabolism Qualified, Suspension
T0123	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Primary Rabbit (New Zealand White) Hepatocytes, Suspension
T0115	ABM	5x10^5 cells / 1.0 ml	EUR 1375

Rat Liver PrimaCell: Hepatocytes
2-82595	CHI Scientific	1 Kit	Ask for price

Mouse Liver PrimaCell: Hepatocytes
2-82100	CHI Scientific	1 Kit	Ask for price

Human Liver PrimaCell: Hepatocytes
2-96121	CHI Scientific	1 Kit	Ask for price

Rat Liver PrimaCell: Normal Hepatocytes Growth Medium
9-25095	CHI Scientific	5 x 100 ml	Ask for price

Mouse Liver PrimaCell: Normal Hepatocytes Growth Medium
9-32100	CHI Scientific	5 x 100 ml	Ask for price

Human Liver PrimaCell: Normal Hepatocytes Growth Medium
9-46121	CHI Scientific	5 x 100 ml	Ask for price

Rat Hepatocytes
ABC-TC4136	AcceGen	1 vial	Ask for price
For research use only
Description: Rat Hepatocytes (RH) are isolated from adult rat livers. They are cryopreserved at the end of primary cell isolation.

Human Hepatocytes
ABC-TC3646	AcceGen	1 vial	Ask for price
For research use only
Description: The liver fulfills many vital processes in mammals. It is the central organ of energy metabolism, biotransformation of xenobiotics, and synthesis of plasma proteins under physiological and pathophysiological conditions. Primary human hepatocyte culture is an important experimental model for the study of liver specific function. Propagation of human hepatocytes is critical for gene therapy, cell transplantation and clinical liver support systems. In appropriate culture condition, cultured human hepatocytes proliferate and maintain differentiated hepatocyte function such as the synthesis of serum proteins. HH from Gentaur Research Laboratories are isolated from human liver. HH are cryopreserved immediately after purification and delivered frozen. Each vial contains 1 x 10^6 cells in 1 ml volume. HH are characterized by immunofluorescent method with antibodies to albumin, cytokeratin-18 and vimentin. HH are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HH is not recommended for expanding or long term cultures since the cells do not proliferate in culture.

Mouse Hepatocytes
ABC-TC3928	AcceGen	1 vial	Ask for price
For research use only
Description: Our High Quality Mouse Hepatocytes have been isolated from mouse livers after liver perfusion and low-speed differential centrifugation. The hepatocytes are cryoperserved immediately after the experimental process and delivered frozen.

Human Hepatocytes
HC4230	Neuromics	500,000 Cells	EUR 991.2

Human Hepatocytes
CSC-C1495	Creative Bioarray	One Frozen vial	Ask for price

Human Hepatocytes
ALHE33	Alphabioregen	1ml frozen Vial	EUR 620

Bovine Hepatocytes
ABC-TC3132	AcceGen	1 vial	Ask for price
For research use only
Description: Bovine hepatocytes, 4-week bovine

Liver Dissociation System 2 (Hepatocytes, Parenchymal hepatocytes), Mouse and Rat
4-20302	CHI Scientific	ea	Ask for price

Rabbit Liver Hepatocytes
ABC-TC4061	AcceGen	1 vial	Ask for price
For research use only
Description: Rabbit liver epithelial cells, 5-week rabbit

Rat Plateable Hepatocytes
ABC-TC4024	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request.

Rat Liver PrimaCell: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium)
9-26095	CHI Scientific	1 Set	Ask for price

Plateable Mouse Hepatocytes
ABC-TC4023	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request.

Mouse Liver PrimaCell: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium)
9-33100	CHI Scientific	1 Set	Ask for price

Human Liver PrimaCell: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium)
9-47121	CHI Scientific	1 Set	Ask for price

Immortalized human hepatocytes
ABI-TC3500	AcceGen	1 vial	Ask for price
Description: The cell line was prepared by immortalizing hepatocytes from a 12 year-old Caucasian female donor with the SV40 large T antigen. The donor tested negative for CMV, HIV, HBV, and HCV.

Immortalized Monkey Hepatocytes
CSC-I2072Z	Creative Bioarray	One Frozen vial	Ask for price

Human iPSC-derived Hepatocytes
CSC-00863L	Creative Bioarray	One Frozen vial	Ask for price
iPSC-derived Cells

Human Hepatocytes - Opioid Addicted
HC4230OP	Neuromics	500000	EUR 1148.4

Human Hepatocytes - Opioid Addicted
HC4230OP-B	Neuromics	each	EUR 805.5

Immortalized Rat Hepatocytes - SV40
T0078	ABM	1x106 cells / 1.0 ml	EUR 3950

Human Fresh Hepatocytes, Suspension
ABC-TC3432	AcceGen	1 vial	Ask for price
For research use only
Description: Freshly isolated human hepatocytes represent a living biological system in which to measure metabolism, induction, toxicity, and transporter studies.

Rat Hepatocytes Suspension-Adult
ABC-TC4137	AcceGen	1 vial	Ask for price
For research use only
Description: Rat Hepatocytes Suspension - Adult

Human Hepatocytes - Alcohol Addicted
HC4230AA	Neuromics	500,000 Cells	EUR 1148.4

Human Hepatocytes - Alcohol Addicted
HC4230AA-B	Neuromics	each	EUR 625.5

Immortalized Human Hepatocytes - Ras
T0059	ABM	1x106 cells / 1.0 ml	Ask for price

Human Pooled Hepatocytes(Heps 10)
ABC-TC3458	AcceGen	1 vial	Ask for price
For research use only
Description: Human Pooled Primary Hepatocytes (Heps) provide an ideal culture model for drug testing and drug development.Heps 20 Human Pooled Primary Hepatocytes contain cryopreserved hepatocytes pooled from 20 different donors and have undergone only one freeze cycle. Pooled hepatocytes provide the genetic diversity necessary for superior reliability and predictability of the metabolic characteristics of a test compound relative to a representative population. Pooled hepatocytes increase experimental control and reduce costs by eliminating the need to conduct redundant experiments necessary to obtain population-based data. Each lot has undergone a single freeze cycle, assuring maximum hepatocyte viability and consistency from donor to donor within the pool.Cell Features:Each donor's hepatocytes have been cryopreserved ONCE immediately after isolation and purification.Pools of 10 or 20 donors are available. Each donor is represented by a statistically significant number of cells relative to the pool.There is extensive quality control providing characterization of viability and enzyme activity from both individual donors and the total pool.Gentaur guarantees performance and quality.Donor information is available.

Human Pooled Hepatocytes(Heps 20)
ABC-TC3459	AcceGen	1 vial	Ask for price
For research use only
Description: Human Pooled Primary Hepatocytes (HP2 Heps) provide an ideal culture model for drug testing and drug development. HP2 10 Human Pooled Primary Hepatocytes contain cryopreserved hepatocytes pooled from 10 different donors and have undergone only one freeze cycle. Pooled hepatocytes provide the genetic diversity necessary for superior reliability and predictability of the metabolic characteristics of a test compound relative to a representative population. Pooled hepatocytes increase experimental control and reduce costs by eliminating the need to conduct redundant experiments necessary to obtain population-based data. Each lot has undergone a single freeze cycle, assuring maximum hepatocyte viability and consistency from donor to donor within the pool.Cell Features:Each donor's hepatocytes have been cryopreserved ONCE immediately after isolation and purification.Pools of 10 or 20 donors are available. Each donor is represented by a statistically significant number of cells relative to the pool.There is extensive quality control providing characterization of viability and enzyme activity from both individual donors and the total pool.Gentaur guarantees performance and quality.Donor information is available.

Immortalized Mouse Hepatocytes - SV40
T0101	ABM	1x106 cells / 1.0 ml	EUR 3950

Immortalized Human Hepatocytes - hTERT
T0058	ABM	1x106 cells / 1.0 ml	Ask for price

Immortalize Human Hepatocytes-SV40
CSC-I9016L	Creative Bioarray	One Frozen vial	Ask for price

Immortalized Hamster Hepatocytes (SV40)
T0072	ABM	1x10^6 cells / 1.0 ml	Ask for price

Immortalized Mouse Hepatocytes-SV40
CSC-I2205Z	Creative Bioarray	One Frozen vial	Ask for price

Immortalized Monkey Hepatocytes-SV40
T0073	ABM	1x106 cells / 1.0 ml	EUR 3950

Human Hepatocytes-Single Donor, Male
ABC-TC3649	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur's hepatocytes for suspension assays (HP1 Heps-s - single donor, male) provide an economic source of characterized human hepatocytes for use in short-term suspension assays to evaluate the metabolism of drug candidates. Gentaur's hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available.

Cryo Rat (Wistar) Hepatocytes, Plateable
LORICP01	Westburg	each	EUR 552.24

Cryo Monkey (Cyno) Hepatocytes, Plateable
LOCYCP01	Westburg	each	EUR 965.52

Cryo Rat (Wistar) Hepatocytes, Suspension
LORICS01	Westburg	each	EUR 328.97

Human Hepatocytes-Single Donor, Female
ABC-TC3647	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur's hepatocytes for suspension assays (HP1 Heps-s, single donor, female) provide an economic source of characterized human hepatocytes for use in short-term suspension assays to evaluate the metabolism of drug candidates. Gentaur's hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available.

Cryo Monkey (Cyno) Hepatocytes, Suspension
LOCYCS01	Westburg	each	EUR 517.8

HighQC™ Mouse Hepatocytes Stem Cell
ABC-SC0041	AcceGen	1 vial	Ask for price
Description: Mouse Hepatocyte Stem Cells; Frozen Vial and Plated cells are available. Cells are only guaranteed with purchase of Gentaur Media and Gentaur Extra Cellular Matrix for appropriate cell culture, for 30 days from the date of shipment.

Cryo Mouse (CD-1) Hepatocytes, Pltable
LOMCCP01	Westburg	each	EUR 1102.09

Human Mature Hepatocytes, Non-Plateable
ABC-TC3893	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request.

Cryo Monkey (Rhesus) Hepatocytes, Plateable
LORHCP01	Westburg	each	EUR 965.52

Cryo monkey (Rhesus) Hepatocytes, Suspension
LORHCS01	Westburg	each	EUR 517.8

Immortalized Sprague Dawley Rats Hepatocytes
ABI-TC047D	AcceGen	1 vial	Ask for price
Description: Sprague Dawley rats hepatocytes conditionally Immortalised with temperature sensitive SV40 large T antigen.

HighQC™ Human IPSC-Derived Hepatocytes
ABC-SC2119	AcceGen	1 vial	Ask for price
Description: These hepatocytes overcome the functionality, reproducibility, and availability limitations of existing primary cell and tumor-derived cell models by providing the following:Relevant hepatic functionality and phenotypic stabilityExpression of clinical targets that are relevant for liver and metabolic diseaseCompatibility with a wide range of 3D and microphysiological systemsQuality-controlled manufacturing and batch reproducibilityReady supply in a cryopreserved format

MCHT50 - Cryo Human Hepatocytes thawing media
LOMCHT50	Westburg	each	EUR 102.95

Immortalized Monkey Hepatocytes-SV40 T+t
T0074	ABM	1x106 cells / 1.0 ml	EUR 3950

C57BL/6 Mouse Hepatocytes Suspension-Adult
ABC-TC3192	AcceGen	1 vial	Ask for price
For research use only
Description: C57BL/6 Mouse Hepatocytes Suspension - Adult

Human Plateable Hepatocytes From Whole Livers
ABC-TC4022	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request.

Cryo Rat (Sprague Dawley) Hepatocytes, Plateable
LORSCP01	Westburg	each	EUR 552.24

Immortalized Hamster Hepatocytes-SV40 T+t
T0071	ABM	1x106 cells / 1.0 ml	EUR 3950

Liver Dissociation System 1 (Hepatocytes), Mouse
4-20301	CHI Scientific	ea	Ask for price

Cryo Rat (Sprague Dawley) Hepatocytes, Suspension
LORSCS01	Westburg	each	EUR 328.97

Cryo Rat (Wistar Hannover) Hepatocytes, Plateable
LORWCP01	Westburg	each	EUR 552.24

Wistar male rat HEPATOCYTES , 10 million cells
LORIFS10-EU	Westburg	each	Ask for price

Conditionally Immortalized Rat Hepatocytes-SV40T
CSC-I2094Z	Creative Bioarray	One Frozen vial	Ask for price

Human Hepatocytes-Single Donor, Male; Inducible
ABC-TC3650	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur's inducible hepatocytes (HP1 Heps-i, single donor, male) can be plated and used in long-term drug induction studies or metabolic studies where long-term incubations are required. Gentaur's cryopreserved primary human hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is tested for plating and provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available.

Cryo Rat (Wistar Hannover) Hepatocytes, Suspension
LORWCS01	Westburg	each	EUR 328.97

Immortalized Mouse Hepatocytes-Conditionally (ImHep)
T0099	ABM	1x106 cells / 1.0 ml	EUR 3950

Human Hepatocytes-Single Donor, Female; Inducible
ABC-TC3648	AcceGen	1 vial	Ask for price
For research use only
Description: Gentaur's inducible hepatocytes (HP1 Heps-i, single donor, female) can be plated and used in long-term drug induction studies or metabolic studies where long-term incubations are required. Gentaur's cryopreserved primary human hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is tested for plating and provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available.

Dog Primary hepatic carcinoma ELISA kit
E08P0656-192T	BlueGene	192 tests	EUR 1524
Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT Show more
Description: A competitive ELISA for quantitative measurement of Canine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Primary hepatic carcinoma ELISA kit
E08P0656-48	BlueGene	1 plate of 48 wells	EUR 624
Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT Show more
Description: A competitive ELISA for quantitative measurement of Canine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Primary hepatic carcinoma ELISA kit
E08P0656-96	BlueGene	1 plate of 96 wells	EUR 822
Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT Show more
Description: A competitive ELISA for quantitative measurement of Canine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Immortalized Human Hepatocytes - HPVE6/E7 and Myc
T0057	ABM	1x10^6 cells / 1.0 ml	EUR 350

Liver Dissociation System 4 (Hepatocytes, rat), Rat
4-20304	CHI Scientific	ea	Ask for price

Human hepatocytes in suspension , 10 million cells
LOHUFS10-EU	Westburg	each	Ask for price

Male Cynomolgus monkey HEPATOCYTES , 10 million cells
LOCYFS10-EU	Westburg	each	Ask for price

Beagle dog Plasma (Sterile Sodium Heparin)
20-abx800100	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1 month.

Beagle dog Plasma (Sterile Sodium Heparin)
abx800100-1L	Abbexa	1 L	EUR 10466.4
Shipped within 1 month.

Beagle dog Plasma (Sterile Sodium Heparin)
abx800100-10nmol	Abbexa	10 nmol	EUR 2162.5

Beagle dog Plasma (Sterile Sodium Heparin)
abx800100-5nmol	Abbexa	5 nmol	EUR 1262.5

Rat Liver Tissue Preparation Buffer: Normal Hepatocytes
9-80322	CHI Scientific	1 x 100 ml	Ask for price

Immortalized Human Hepatocytes - HPV E6/E7, hTERT & MycT58A
T0063	ABM	1x10^6 cells / 1.0 ml	EUR 350

Mouse Liver Tissue Preparation Buffer: Normal Hepatocytes
9-80306	CHI Scientific	1 x 100 ml	Ask for price

Human Liver Tissue Preparation Buffer: Normal Hepatocytes
9-80314	CHI Scientific	1 x 100 ml	Ask for price

Beagle dog Whole Blood (Sterile Sodium Heparin)
20-abx800106	Abbexa	Ask for price Ask for price	100 ml 50 ml
Shipped within 1-5 working days.

Beagle dog Whole Blood (Sterile Sodium Heparin)
abx800106-10nmol	Abbexa	10 nmol	EUR 2000

Beagle dog Whole Blood (Sterile Sodium Heparin)
abx800106-5nmol	Abbexa	5 nmol	EUR 1100

Beagle dog Plasma (Non-Sterile Sodium Heparin)
20-abx800099	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1 month.

Beagle dog Plasma (Non-Sterile Sodium Heparin)
abx800099-1L	Abbexa	1 L	EUR 7910.4
Shipped within 1 month.

Beagle dog Plasma (Non-Sterile Sodium Heparin)
abx800099-10nmol	Abbexa	10 nmol	EUR 2000

Beagle dog Plasma (Non-Sterile Sodium Heparin)
abx800099-5nmol	Abbexa	5 nmol	EUR 1200

Hepatocytes of male Wistar rat in monolayer, in 6 well-plate
LORIF06-EU	Westburg	each	Ask for price

Hepatocytes of male Wistar rat in monolayer, in 12 well-plate
LORIF12-EU	Westburg	each	Ask for price

Hepatocytes of male Wistar rat in monolayer, in 24 well-plate
LORIF24-EU	Westburg	each	Ask for price

Hepatocytes of male Wistar rat in monolayer, in 48 well-plate
LORIF48-EU	Westburg	each	Ask for price

Hepatocytes of male Wistar rat in monolayer, in 96 well-plate
LORIF96-EU	Westburg	each	Ask for price

Male Cynomolgus monkey HEPATOCYTES in monolayer, in 6 well-plate
LOCYF06-EU	Westburg	each	Ask for price

Male Cynomolgus monkey HEPATOCYTES in monolayer, in 12 well-plate
LOCYF12-EU	Westburg	each	Ask for price

Male Cynomolgus monkey HEPATOCYTES in monolayer, in 24 well-plate
LOCYF24-EU	Westburg	each	Ask for price

Male Cynomolgus monkey HEPATOCYTES in monolayer, in 48 well-plate
LOCYF48-EU	Westburg	each	Ask for price

Liver Dissociation System 6 (Hepatocytes,Nonparenchymal), Mouse and Rat
4-20306	CHI Scientific	ea	Ask for price

Beagle dog Serum Sterile
20-abx800094	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1-5 working days.

Beagle dog Serum Sterile
abx800094-1L	Abbexa	1 L	EUR 9096
Shipped within 1-5 working days.

Beagle dog Serum Sterile
abx800094-10nmol	Abbexa	10 nmol	EUR 2162.5

Beagle dog Serum Sterile
abx800094-5nmol	Abbexa	5 nmol	EUR 1262.5

Beagle dog Whole Blood (Non-Sterile Sodium Heparin)
20-abx800105	Abbexa	Ask for price Ask for price	100 ml 50 ml
Shipped within 1-5 working days.

Beagle dog Whole Blood (Non-Sterile Sodium Heparin)
abx800105-10nmol	Abbexa	10 nmol	EUR 1800

Beagle dog Whole Blood (Non-Sterile Sodium Heparin)
abx800105-5nmol	Abbexa	5 nmol	EUR 1000

Hepatocytes of male Sprague Dawley rat in monolayer, in 6 well plate
LORSF06-EU	Westburg	each	Ask for price

Hepatocytes of male Sprague Dawley rat in monolayer, in 12 well plate
LORSF12-EU	Westburg	each	Ask for price

Hepatocytes of male Sprague Dawley rat in monolayer, in 24 well plate
LORSF24-EU	Westburg	each	Ask for price

Hepatocytes of male Sprague Dawley rat in monolayer, in 48 well plate
LORSF48-EU	Westburg	each	Ask for price

Hepatocytes of male Sprague Dawley rat in monolayer, in 96 well plate
LORSF96-EU	Westburg	each	Ask for price

Hepatocytes of male Sprague Dawley rat in suspension , 10 million cells
LORSFS10-EU	Westburg	each	Ask for price

Human hepatocytes in monolayer-long term cultures, in 6 well-plate
LOHUF06-EU	Westburg	each	Ask for price

Human hepatocytes in monolayer-long term cultures, in 12 well-plate
LOHUF12-EU	Westburg	each	Ask for price

Human hepatocytes in monolayer-long term cultures, in 24 well-plate
LOHUF24-EU	Westburg	each	Ask for price

Human hepatocytes in monolayer-long term cultures, in 48 well-plate
LOHUF48-EU	Westburg	each	Ask for price

Human hepatocytes in monolayer-long term cultures, in 96 well-plate
LOHUF96-EU	Westburg	each	Ask for price

Liver Dissociation System 3 (Hepatocytes, Kupffer, Parenchymal), Mouse and Rat
4-20303	CHI Scientific	ea	Ask for price

Beagle dog Serum (Non-Sterile)
20-abx800093	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1-5 working days.

Beagle dog Serum (Non-Sterile)
abx800093-1L	Abbexa	1 L	EUR 7108.8
Shipped within 1-5 working days.

Beagle dog Serum (Non-Sterile)
abx800093-10nmol	Abbexa	10 nmol	EUR 2000

Beagle dog Serum (Non-Sterile)
abx800093-5nmol	Abbexa	5 nmol	EUR 1200

Beagle dog Red Blood Cells (100%)
20-abx800107	Abbexa	Ask for price Ask for price	100 ml 50 ml
Shipped within 1-5 working days.

Beagle dog Red Blood Cells (100%)
abx800107-10nmol	Abbexa	10 nmol	EUR 2300

Beagle dog Red Blood Cells (100%)
abx800107-5nmol	Abbexa	5 nmol	EUR 1312.5

Beagle dog Plasma (Sterile Sodium EDTA)
20-abx800098	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1 month.

Beagle dog Plasma (Sterile Sodium EDTA)
abx800098-1L	Abbexa	1 L	EUR 10466.4
Shipped within 1 month.

Beagle dog Plasma (Sterile Sodium EDTA)
abx800098-10nmol	Abbexa	10 nmol	EUR 2162.5

Beagle dog Plasma (Sterile Sodium EDTA)
abx800098-5nmol	Abbexa	5 nmol	EUR 1262.5

Beagle dog Plasma (Sterile Sodium Citrate)
20-abx800096	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1 month.

Beagle dog Plasma (Sterile Sodium Citrate)
abx800096-1L	Abbexa	1 L	EUR 10466.4
Shipped within 1 month.

Beagle dog Plasma (Sterile Sodium Citrate)
abx800096-10nmol	Abbexa	10 nmol	EUR 2162.5

Beagle dog Plasma (Sterile Sodium Citrate)
abx800096-5nmol	Abbexa	5 nmol	EUR 1262.5

Beagle dog Whole Blood (Sterile Sodium EDTA)
20-abx800104	Abbexa	Ask for price Ask for price	100 ml 50 ml
Shipped within 1-5 working days.

Beagle dog Whole Blood (Sterile Sodium EDTA)
abx800104-10nmol	Abbexa	10 nmol	EUR 2000

Beagle dog Whole Blood (Sterile Sodium EDTA)
abx800104-5nmol	Abbexa	5 nmol	EUR 1100

Beagle dog Plasma (Non-Sterile Sodium EDTA)
20-abx800097	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1 month.

Beagle dog Plasma (Non-Sterile Sodium EDTA)
abx800097-1L	Abbexa	1 L	EUR 7910.4
Shipped within 1 month.

Beagle dog Plasma (Non-Sterile Sodium EDTA)
abx800097-10nmol	Abbexa	10 nmol	EUR 2000

Beagle dog Plasma (Non-Sterile Sodium EDTA)
abx800097-5nmol	Abbexa	5 nmol	EUR 1200

Beagle dog Whole Blood (Sterile Sodium Citrate)
20-abx800102	Abbexa	Ask for price Ask for price	100 ml 50 ml
Shipped within 1-5 working days.

Beagle dog Whole Blood (Sterile Sodium Citrate)
abx800102-10nmol	Abbexa	10 nmol	EUR 2000

Beagle dog Whole Blood (Sterile Sodium Citrate)
abx800102-5nmol	Abbexa	5 nmol	EUR 1100

Beagle dog Plasma (Non-Sterile Sodium Citrate)
20-abx800095	Abbexa	Ask for price Ask for price Ask for price	100 ml 500 ml 50 ml
Shipped within 1 month.

Beagle dog Plasma (Non-Sterile Sodium Citrate)
abx800095-1L	Abbexa	1 L	EUR 7910.4
Shipped within 1 month.

Beagle dog Plasma (Non-Sterile Sodium Citrate)
abx800095-10nmol	Abbexa	10 nmol	EUR 2000

Beagle dog Plasma (Non-Sterile Sodium Citrate)
abx800095-5nmol	Abbexa	5 nmol	EUR 1200

Dog Hepatocyte Growth Factor ELISA kit
E08H0208-192T	BlueGene	192 tests	EUR 1524
Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT Show more
Description: A competitive ELISA for quantitative measurement of Canine Hepatocyte Growth Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Hepatocyte Growth Factor ELISA kit
E08H0208-48	BlueGene	1 plate of 48 wells	EUR 624
Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT Show more
Description: A competitive ELISA for quantitative measurement of Canine Hepatocyte Growth Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Hepatocyte Growth Factor ELISA kit
E08H0208-96	BlueGene	1 plate of 96 wells	EUR 822
Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT Show more
Description: A competitive ELISA for quantitative measurement of Canine Hepatocyte Growth Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Hepatocyte growth factor ELISA Kit
MBS9424989-5x96Tests	MyBiosource	5x96Tests	EUR 2985

Dog Hepatocyte growth factor ELISA Kit
MBS9424989-96Tests	MyBiosource	96Tests	EUR 650

Dog Hepatocyte growth factor ELISA Kit
MBS2880226-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 4080

Dog Hepatocyte growth factor ELISA Kit
MBS2880226-48StripWells	MyBiosource	48-Strip-Wells	EUR 390

Dog Hepatocyte growth factor ELISA Kit
MBS2880226-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 2220

Dog Hepatocyte growth factor ELISA Kit
MBS2880226-96StripWells	MyBiosource	96-Strip-Wells	EUR 520

Dog Primary CD3+ Pan T Cells
T5495	ABM	1x10^6 cells / 1.0 ml	EUR 1425

Dog Primary CD3+ Pan T Cells
T5496	ABM	1x10^6 cells / 1.0 ml	EUR 1425

Dog Primary CD3+ Pan T Cells
T5497	ABM	1x10^6 cells / 1.0 ml	EUR 1425

Dog Hepatocyte Growth Factor (HGF) Protein
20-abx166357	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug
Shipped within 5-7 working days.

Dog Hepatocyte Growth Factor (HGF) Protein
abx166357-100g	Abbexa	100 µg	EUR 775

Dog Hepatocyte Growth Factor (HGF) Protein
abx166357-10g	Abbexa	10 µg	EUR 437.5

Dog Hepatocyte Growth Factor (HGF) Protein
abx166357-50g	Abbexa	50 µg	EUR 637.5

Primary Rat Hepatic Stellate Cells (HSC)
CSI071Ra01	Cloud-Clone	5X10^5	EUR 880
Rat

Dog Hepatocyte Growth Factor (HGF) CLIA Kit
20-abx190801	Abbexa	Ask for price Ask for price Ask for price	10 × 96 tests 5 × 96 tests 96 tests
Shipped within 5-7 working days.

Dog Hepatocyte Growth Factor (HGF) CLIA Kit
EKN50850-48T	Biomatik Corporation	48T	EUR 474.18

Dog Hepatocyte Growth Factor (HGF) CLIA Kit
EKN50850-5x96T	Biomatik Corporation	5x96T	EUR 3217.65

Dog Hepatocyte Growth Factor (HGF) CLIA Kit
EKN50850-96T	Biomatik Corporation	96T	EUR 677.4

Dog Hepatocyte Growth Factor (HGF) CLIA Kit
EKU09739-48T	Biomatik Corporation	48T	EUR 762.02

Particularly, main rat hepatocytes had been cocultured with NIH-3T3 fibroblasts on mushy (2 kPa) and stiff substrates that recreates physiologic (2 kPa) and cirrhotic liver stiffness (55 kPa). Urea synthesis by main hepatocytes trusted the presence of fibroblast and was unbiased of the substrate stiffness. Nevertheless, albumin synthesis and Cytochrome P450 enzyme exercise elevated in hepatocytes on mushy substrates and when in coculture with a fibroblast. Western blot evaluation of hepatic markers, E-cadherin, confirmed that hepatocytes on mushy substrates in coculture promoted higher upkeep of the hepatic phenotype. These findings point out the position of stiffness in regulating the hepatocytes interactions with NPCs mandatory for upkeep of hepatocytes perform.