The rising extraction of uncommon earth components (REEs) for know-how purposes raised considerations for contamination and toxicity within the atmosphere. The aim of this research was to look at the toxicity of the next REEs in main cultures of rainbow trout hepatocytes: yttrium (Y), samarium (Sm), gadolinium (Gd), terbium (Tb) and lutetium (Lu). Hepatocytes had been uncovered to rising concentrations of the above components for 24 h at 15 °C they usually had been analyzed for viability, metallothioneins (MT), glutathione-S-transferase (GST) and arachidonate cyclooxygenase (COX) as markers of oxidative stress and irritation.
The outcomes revealed that the cytoxicity of REEs had been as follows in reducing order: Y > Sm > Lu > Tb > Gd as with revealed m in rainbow trout. Whereas results on GST and COX actions had been marginal, MT ranges had been extra strongly elevated with the two most poisonous REEs (Y and Sm) and Gd, whereas MT ranges had been decreased within the least poisonous ones (Tb, Lu).
Whereas cell viability adopted revealed trout mortality information, it additionally adopted the redox potential and the glutathione affinity fixed (log ok). The capability to induce/lower MT ranges was related to ionic radius, log ok (glutathione) and electronegativity. A proposed mechanism of toxicity for REEs is offered based mostly on the chemical properties of REEs, particularly the glutathione binding fixed and ionic radius, in mild of the noticed results in trout hepatocytes.
Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells within the liver
Hepatocellular carcinoma (HCC) is pushed by repeated rounds of irritation, resulting in fibrosis, cirrhosis, and, finally, most cancers. A important step in HCC formation is the transition from fibrosis to cirrhosis, which is related to a change within the liver parenchyma known as ductular response. Right here, we report a genetically engineered mouse mannequin of HCC pushed by lack of macroautophagy and hemizygosity of phosphatase and tensin homolog, which develops HCC involving ductular response. We present by means of lineage tracing that, following lack of autophagy, mature hepatocytes dedifferentiate into biliary-like liver progenitor cells (ductular response), giving rise to HCC.
Moreover, this variation is related to deregulation of yes-associated protein and transcriptional coactivator with PDZ-binding motif transcription elements, and the mixed, however not particular person, deletion of those elements fully reverses the dedifferentiation capability and tumorigenesis. These findings due to this fact improve our understanding of the cell of origin of HCC growth and spotlight new potential factors for therapeutic intervention.
Lymphotoxin-β-receptor (LTβR) signaling on hepatocytes is required for liver regeneration after partial hepatectomy
Lymphotoxin-β-receptor poor (LTβR
-/-) and Tumor Necrosis Issue Receptor p55 poor (
parafina) mice present defects in liver regeneration (LR) after partial hepatectomy (PHx) with considerably elevated mortality. LTβR and TNFRp55 belong to the core members of the TNF/TNFR superfamily. Apparently, mixed failure of LTβR and TNFRp55 signaling after PHx leads to a whole defect in LR. Right here, we first addressed the query which liver cell inhabitants crucially requires LTβR signaling for environment friendly LR.
To this finish, mice with a conditionally focused LTβR allele (LTβRfl/fl) had been crossed to AlbuminCre and LysozymeMCre mouse traces to unravel the perform of the LTβR on hepatocytes and monocytes/macrophages/Kupffer cells, respectively. Evaluation of those mouse traces clearly reveals that LTβR is required on hepatocytes for environment friendly LR whereas no deficit in LR was present in LTβRfl/fl × LysMCre mice.
Second, the molecular foundation for the cooperating position of LTβR and TNFRp55 signaling pathways in LR was investigated by transcriptome evaluation of etanercept handled LTβR-/- (LTβR-/-/ET) mice. Bioinformatic evaluation and subsequent verification by qRT-PCR recognized novel goal genes (Cyclin-L2, Fas-Binding issue 1, interferon-related developmental regulator 1, Leucyl-tRNA Synthetase 2, and galectin-4) which might be upregulated by LTβR/TNFRp55 signaling after PHx and fail to be upregulated after PHx in LTβR-/-/ET mice.
Exploring Interactions between Main Hepatocytes and Non-Parenchymal Cells on Physiological and Pathological Liver Stiffness
Power liver illness is characterised by progressive hepatic fibrosis resulting in the formation of cirrhosis regardless of the etiology with no efficient therapy at the moment accessible. Liver stiffness (LS) is at the moment the very best medical predictor of this fibrosis development regardless of the etiology. LS and hepatocytes-nonparenchymal cells (NPC) interactions are two variables recognized to be essential in regulating hepatic perform throughout liver fibrosis, however little is understood concerning the interaction of those cues. Right here, we use polydimethyl siloxane (PDMS) based mostly substrates with tunable mechanical properties to review how cell-cell interplay and stiffness regulates hepatocytes perform.
 Hepatocytes, Suspension) Cryo Dog (Beagle) Hepatocytes, Suspension |
|
LODBCS01 |
Westburg |
each |
EUR 390.63 |
 Male Beagle dog HEPATOCYTES , 10 million cells |
|
LODBFS10-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Beagle dog in monolayer, in 6 well-plate |
|
LODBF06-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Beagle dog in monolayer, in 12 well-plate |
|
LODBF12-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Beagle dog in monolayer, in 24 well-plate |
|
LODBF24-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Beagle dog in monolayer, in 48 well-plate |
|
LODBF48-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Beagle dog in monolayer, in 96 well-plate |
|
LODBF96-EU |
Westburg |
each |
Ask for price |
 Hepatocytes, Plateable) Primary Rat (Fischer) Hepatocytes, Plateable |
|
T0108 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Normal Human Primary Plateable Hepatocytes |
|
T5539 |
ABM |
1x10^6 cells / 1.0 ml |
EUR 925 |
Normal Human Primary Plateable Hepatocytes |
|
T5541 |
ABM |
1x10^6 cells / 1.0 ml |
Ask for price |
 Hepatocytes, Suspension) Primary Rat (Fischer) Hepatocytes, Suspension |
|
T0107 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Normal Human Primary Suspension Hepatocytes |
|
T5538 |
ABM |
1x10^6 cells / 1.0 ml |
Ask for price |
 Hepatocytes, Plateable) Primary Mouse (CD-1) Hepatocytes, Plateable |
|
T0120 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Suspension) Primary Mouse (CD-1) Hepatocytes, Suspension |
|
T0119 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 hepatocytes, Plateable) Primary Monkey (Cynomolgus) hepatocytes, Plateable |
|
T0112 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Plateable) Primary Rat (Wistar Han) Hepatocytes, Plateable |
|
T0106 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Plateable) Primary Mouse (C57BI/6) Hepatocytes, Plateable |
|
T0122 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Suspension) Primary Monkey (Cynomolgus) Hepatocytes, Suspension |
|
T0111 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Suspension) Primary Minipig (Gottingen) Hepatocytes, Suspension |
|
T0113 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Suspension) Primary Rat (Wistar Han) Hepatocytes, Suspension |
|
T0105 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Suspension) Primary Mouse (C57BI/6) Hepatocytes, Suspension |
|
T0121 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Enhanced Primary Human Hepatocytes - 5 million |
|
T5996 |
ABM |
5x10^6 cells / 1.0 ml |
Ask for price |
 Hepatocytes, Plateable) Primary Rat (Sprague Dawley) Hepatocytes, Plateable |
|
T0104 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Suspension) Primary Rat (Sprague Dawley) Hepatocytes, Suspension |
|
T0103 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Enhanced Primary Human Hepatocytes – 1 Million |
|
T5995 |
ABM |
1x10^6 cells / 1.0ml |
Ask for price |
 Primary Human Hepatocytes, Transporter Uptake Qualified |
|
T0125 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 3500 |
 Primary Human Hepatocytes, Induction Qualified, Plateable |
|
T0128 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 2625 |
 Primary Human Hepatocytes, Metabolism Qualified, Plateable |
|
T0124 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 2625 |
 Primary Human Hepatocytes, Metabolism Qualified, Suspension |
|
T0123 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Hepatocytes, Suspension) Primary Rabbit (New Zealand White) Hepatocytes, Suspension |
|
T0115 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
 Rat Liver PrimaCell™: Hepatocytes |
|
2-82595 |
CHI Scientific |
1 Kit |
EUR 1039.5 |
 Mouse Liver PrimaCell™: Hepatocytes |
|
2-82100 |
CHI Scientific |
1 Kit |
EUR 1039.5 |
 Human Liver PrimaCell™: Hepatocytes |
|
2-96121 |
CHI Scientific |
1 Kit |
EUR 1132.11 |
 Rat Liver PrimaCell™: Normal Hepatocytes Growth Medium |
|
9-25095 |
CHI Scientific |
5 x 100 ml |
EUR 122.85 |
 Rat Hepatocytes |
|
ABC-TC4136 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Rat Hepatocytes (RH) are isolated from adult rat livers. They are cryopreserved at the end of primary cell isolation. |
 Mouse Liver PrimaCell™: Normal Hepatocytes Growth Medium |
|
9-32100 |
CHI Scientific |
5 x 100 ml |
EUR 122.85 |
 Human Liver PrimaCell™: Normal Hepatocytes Growth Medium |
|
9-46121 |
CHI Scientific |
5 x 100 ml |
EUR 151.2 |
 Human Hepatocytes |
|
ABC-TC3646 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: The liver fulfills many vital processes in mammals. It is the central organ of energy metabolism, biotransformation of xenobiotics, and synthesis of plasma proteins under physiological and pathophysiological conditions. Primary human hepatocyte culture is an important experimental model for the study of liver specific function. Propagation of human hepatocytes is critical for gene therapy, cell transplantation and clinical liver support systems. In appropriate culture condition, cultured human hepatocytes proliferate and maintain differentiated hepatocyte function such as the synthesis of serum proteins. HH from Gentaur Research Laboratories are isolated from human liver. HH are cryopreserved immediately after purification and delivered frozen. Each vial contains 1 x 10^6 cells in 1 ml volume. HH are characterized by immunofluorescent method with antibodies to albumin, cytokeratin-18 and vimentin. HH are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HH is not recommended for expanding or long term cultures since the cells do not proliferate in culture. |
 Mouse Hepatocytes |
|
ABC-TC3928 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Our High Quality Mouse Hepatocytes have been isolated from mouse livers after liver perfusion and low-speed differential centrifugation. The hepatocytes are cryoperserved immediately after the experimental process and delivered frozen. |
Human Hepatocytes |
|
HC4230 |
Neuromics |
500,000 Cells |
EUR 991.2 |
 Bovine Hepatocytes |
|
ABC-TC3132 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Bovine hepatocytes, 4-week bovine |
, Mouse and Rat) Liver Dissociation System 2 (Hepatocytes, Parenchymal hepatocytes), Mouse and Rat |
|
4-20302 |
CHI Scientific |
ea |
EUR 161.87 |
 Rabbit Liver Hepatocytes |
|
ABC-TC4061 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Rabbit liver epithelial cells, 5-week rabbit |
 Rat Plateable Hepatocytes |
|
ABC-TC4024 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
 Plateable Mouse Hepatocytes |
|
ABC-TC4023 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
 Immortalized human hepatocytes |
|
ABI-TC3500 |
AcceGen |
1 vial |
Ask for price |
|
Description: The cell line was prepared by immortalizing hepatocytes from a 12 year-old Caucasian female donor with the SV40 large T antigen. The donor tested negative for CMV, HIV, HBV, and HCV. |
 Immortalized Monkey Hepatocytes |
|
CSC-I2072Z |
Creative Bioarray |
One Frozen vial |
Ask for price |
 Human iPSC-derived Hepatocytes |
|
CSC-00863L |
Creative Bioarray |
One Frozen vial |
Ask for price |
|
|
 Human Hepatocytes - Opioid Addicted |
|
HC4230OP |
Neuromics |
500000 |
EUR 625.5 |
Human Hepatocytes - Opioid Addicted |
|
HC4230OP-B |
Neuromics |
each |
EUR 805.5 |
 Immortalized Rat Hepatocytes - SV40 |
|
T0078 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
 Human Fresh Hepatocytes, Suspension |
|
ABC-TC3432 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Freshly isolated human hepatocytes represent a living biological system in which to measure metabolism, induction, toxicity, and transporter studies. |
 Rat Hepatocytes Suspension-Adult |
|
ABC-TC4137 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Rat Hepatocytes Suspension - Adult |
 Human Hepatocytes - Alcohol Addicted |
|
HC4230AA |
Neuromics |
500,000 Cells |
EUR 805.5 |
Human Hepatocytes - Alcohol Addicted |
|
HC4230AA-B |
Neuromics |
each |
EUR 625.5 |
 Immortalized Human Hepatocytes - Ras |
|
T0059 |
ABM |
1x106 cells / 1.0 ml |
Ask for price |
) Human Pooled Hepatocytes(Heps 10) |
|
ABC-TC3458 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Human Pooled Primary Hepatocytes (Heps) provide an ideal culture model for drug testing and drug development.Heps 20 Human Pooled Primary Hepatocytes contain cryopreserved hepatocytes pooled from 20 different donors and have undergone only one freeze cycle. Pooled hepatocytes provide the genetic diversity necessary for superior reliability and predictability of the metabolic characteristics of a test compound relative to a representative population. Pooled hepatocytes increase experimental control and reduce costs by eliminating the need to conduct redundant experiments necessary to obtain population-based data. Each lot has undergone a single freeze cycle, assuring maximum hepatocyte viability and consistency from donor to donor within the pool.Cell Features:Each donor's hepatocytes have been cryopreserved ONCE immediately after isolation and purification.Pools of 10 or 20 donors are available. Each donor is represented by a statistically significant number of cells relative to the pool.There is extensive quality control providing characterization of viability and enzyme activity from both individual donors and the total pool.Gentaur guarantees performance and quality.Donor information is available. |
) Human Pooled Hepatocytes(Heps 20) |
|
ABC-TC3459 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Human Pooled Primary Hepatocytes (HP2 Heps) provide an ideal culture model for drug testing and drug development. HP2 10 Human Pooled Primary Hepatocytes contain cryopreserved hepatocytes pooled from 10 different donors and have undergone only one freeze cycle. Pooled hepatocytes provide the genetic diversity necessary for superior reliability and predictability of the metabolic characteristics of a test compound relative to a representative population. Pooled hepatocytes increase experimental control and reduce costs by eliminating the need to conduct redundant experiments necessary to obtain population-based data. Each lot has undergone a single freeze cycle, assuring maximum hepatocyte viability and consistency from donor to donor within the pool.Cell Features:Each donor's hepatocytes have been cryopreserved ONCE immediately after isolation and purification.Pools of 10 or 20 donors are available. Each donor is represented by a statistically significant number of cells relative to the pool.There is extensive quality control providing characterization of viability and enzyme activity from both individual donors and the total pool.Gentaur guarantees performance and quality.Donor information is available. |
 Immortalized Mouse Hepatocytes - SV40 |
|
T0101 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
 Immortalize Human Hepatocytes-SV40 |
|
CSC-I9016L |
Creative Bioarray |
One Frozen vial |
Ask for price |
 Immortalized Human Hepatocytes - hTERT |
|
T0058 |
ABM |
1x106 cells / 1.0 ml |
Ask for price |
 Immortalized Mouse Hepatocytes-SV40 |
|
CSC-I2205Z |
Creative Bioarray |
One Frozen vial |
Ask for price |
) Immortalized Hamster Hepatocytes (SV40) |
|
T0072 |
ABM |
1x10^6 cells / 1.0 ml |
Ask for price |
 Immortalized Monkey Hepatocytes-SV40 |
|
T0073 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
) Rat Liver PrimaCell™: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium) |
|
9-26095 |
CHI Scientific |
1 Set |
EUR 283.5 |
 Human Hepatocytes-Single Donor, Male |
|
ABC-TC3649 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Gentaur's hepatocytes for suspension assays (HP1 Heps-s - single donor, male) provide an economic source of characterized human hepatocytes for use in short-term suspension assays to evaluate the metabolism of drug candidates. Gentaur's hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
 Hepatocytes, Plateable) Cryo Rat (Wistar) Hepatocytes, Plateable |
|
LORICP01 |
Westburg |
each |
EUR 552.24 |
) Mouse Liver PrimaCell™: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium) |
|
9-33100 |
CHI Scientific |
1 Set |
EUR 283.5 |
) Human Liver PrimaCell™: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium) |
|
9-47121 |
CHI Scientific |
1 Set |
EUR 321.3 |
 Hepatocytes, Plateable) Cryo Monkey (Cyno) Hepatocytes, Plateable |
|
LOCYCP01 |
Westburg |
each |
EUR 965.52 |
 Hepatocytes, Suspension) Cryo Rat (Wistar) Hepatocytes, Suspension |
|
LORICS01 |
Westburg |
each |
EUR 328.97 |
 Human Hepatocytes-Single Donor, Female |
|
ABC-TC3647 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Gentaur's hepatocytes for suspension assays (HP1 Heps-s, single donor, female) provide an economic source of characterized human hepatocytes for use in short-term suspension assays to evaluate the metabolism of drug candidates. Gentaur's hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
 Hepatocytes, Suspension) Cryo Monkey (Cyno) Hepatocytes, Suspension |
|
LOCYCS01 |
Westburg |
each |
EUR 517.8 |
 HighQC™ Mouse Hepatocytes Stem Cell |
|
ABC-SC0041 |
AcceGen |
1 vial |
Ask for price |
|
Description: Mouse Hepatocyte Stem Cells; Frozen Vial and Plated cells are available. Cells are only guaranteed with purchase of Gentaur Media and Gentaur Extra Cellular Matrix for appropriate cell culture, for 30 days from the date of shipment. |
 Hepatocytes, Pltable) Cryo Mouse (CD-1) Hepatocytes, Pltable |
|
LOMCCP01 |
Westburg |
each |
EUR 1102.09 |
 Human Mature Hepatocytes, Non-Plateable |
|
ABC-TC3893 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
 Hepatocytes, Plateable) Cryo Monkey (Rhesus) Hepatocytes, Plateable |
|
LORHCP01 |
Westburg |
each |
EUR 965.52 |
 Hepatocytes, Suspension) Cryo monkey (Rhesus) Hepatocytes, Suspension |
|
LORHCS01 |
Westburg |
each |
EUR 517.8 |
 Immortalized Sprague Dawley Rats Hepatocytes |
|
ABI-TC047D |
AcceGen |
1 vial |
Ask for price |
|
Description: Sprague Dawley rats hepatocytes conditionally Immortalised with temperature sensitive SV40 large T antigen. |
 HighQC™ Human IPSC-Derived Hepatocytes |
|
ABC-SC2119 |
AcceGen |
1 vial |
Ask for price |
|
Description: These hepatocytes overcome the functionality, reproducibility, and availability limitations of existing primary cell and tumor-derived cell models by providing the following:Relevant hepatic functionality and phenotypic stabilityExpression of clinical targets that are relevant for liver and metabolic diseaseCompatibility with a wide range of 3D and microphysiological systemsQuality-controlled manufacturing and batch reproducibilityReady supply in a cryopreserved format |
 MCHT50 - Cryo Human Hepatocytes thawing media |
|
LOMCHT50 |
Westburg |
each |
EUR 102.95 |
 Immortalized Monkey Hepatocytes-SV40 T+t |
|
T0074 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
 C57BL/6 Mouse Hepatocytes Suspension-Adult |
|
ABC-TC3192 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: C57BL/6 Mouse Hepatocytes Suspension - Adult |
 Human Plateable Hepatocytes From Whole Livers |
|
ABC-TC4022 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
 Hepatocytes, Plateable) Cryo Rat (Sprague Dawley) Hepatocytes, Plateable |
|
LORSCP01 |
Westburg |
each |
EUR 552.24 |
 Immortalized Hamster Hepatocytes-SV40 T+t |
|
T0071 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
, Mouse) Liver Dissociation System 1 (Hepatocytes), Mouse |
|
4-20301 |
CHI Scientific |
ea |
EUR 144.82 |
 Hepatocytes, Suspension) Cryo Rat (Sprague Dawley) Hepatocytes, Suspension |
|
LORSCS01 |
Westburg |
each |
EUR 328.97 |
 Hepatocytes, Plateable) Cryo Rat (Wistar Hannover) Hepatocytes, Plateable |
|
LORWCP01 |
Westburg |
each |
EUR 552.24 |
 Wistar male rat HEPATOCYTES , 10 million cells |
|
LORIFS10-EU |
Westburg |
each |
Ask for price |
 Conditionally Immortalized Rat Hepatocytes-SV40T |
|
CSC-I2094Z |
Creative Bioarray |
One Frozen vial |
Ask for price |
 Human Hepatocytes-Single Donor, Male; Inducible |
|
ABC-TC3650 |
AcceGen |
1 vial |
Ask for price |
|
|
|
Description: Gentaur's inducible hepatocytes (HP1 Heps-i, single donor, male) can be plated and used in long-term drug induction studies or metabolic studies where long-term incubations are required. Gentaur's cryopreserved primary human hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is tested for plating and provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
 Hepatocytes, Suspension) Cryo Rat (Wistar Hannover) Hepatocytes, Suspension |
|
LORWCS01 |
Westburg |
each |
EUR 328.97 |
) Immortalized Mouse Hepatocytes-Conditionally (ImHep) |
|
T0099 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
 Human Hepatocytes-Single Donor, Female; Inducible |
|
ABC-TC3648 |
AcceGen |
1 vial |
Ask for price |
|
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Description: Gentaur's inducible hepatocytes (HP1 Heps-i, single donor, female) can be plated and used in long-term drug induction studies or metabolic studies where long-term incubations are required. Gentaur's cryopreserved primary human hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is tested for plating and provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
 Immortalized Human Hepatocytes - HPVE6/E7 and Myc |
|
T0057 |
ABM |
1x10^6 cells / 1.0 ml |
EUR 350 |
, Rat) Liver Dissociation System 4 (Hepatocytes, rat), Rat |
|
4-20304 |
CHI Scientific |
ea |
EUR 161.87 |
 Human hepatocytes in suspension , 10 million cells |
|
LOHUFS10-EU |
Westburg |
each |
Ask for price |
 Male Cynomolgus monkey HEPATOCYTES , 10 million cells |
|
LOCYFS10-EU |
Westburg |
each |
Ask for price |
) Beagle dog Plasma (Sterile Sodium Heparin) |
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20-abx800100 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
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Beagle dog Plasma (Sterile Sodium Heparin) |
|
abx800100-10nmol |
Abbexa |
10 nmol |
EUR 2162.5 |
Beagle dog Plasma (Sterile Sodium Heparin) |
|
abx800100-1L |
Abbexa |
1 L |
EUR 10466.4 |
|
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Beagle dog Plasma (Sterile Sodium Heparin) |
|
abx800100-5nmol |
Abbexa |
5 nmol |
EUR 1262.5 |
 Rat Liver Tissue Preparation Buffer: Normal Hepatocytes |
|
9-80322 |
CHI Scientific |
1 x 100 ml |
EUR 132.3 |
 Immortalized Human Hepatocytes - HPV E6/E7, hTERT & MycT58A |
|
T0063 |
ABM |
1x10^6 cells / 1.0 ml |
EUR 350 |
 Mouse Liver Tissue Preparation Buffer: Normal Hepatocytes |
|
9-80306 |
CHI Scientific |
1 x 100 ml |
EUR 132.3 |
 Human Liver Tissue Preparation Buffer: Normal Hepatocytes |
|
9-80314 |
CHI Scientific |
1 x 100 ml |
EUR 160.65 |
) Beagle dog Whole Blood (Sterile Sodium Heparin) |
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20-abx800106 |
Abbexa |
-
Ask for price
-
Ask for price
|
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- Shipped within 1-5 working days.
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Beagle dog Whole Blood (Sterile Sodium Heparin) |
|
abx800106-10nmol |
Abbexa |
10 nmol |
EUR 2000 |
Beagle dog Whole Blood (Sterile Sodium Heparin) |
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abx800106-5nmol |
Abbexa |
5 nmol |
EUR 1100 |
) Beagle dog Plasma (Non-Sterile Sodium Heparin) |
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20-abx800099 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
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|
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Beagle dog Plasma (Non-Sterile Sodium Heparin) |
|
abx800099-10nmol |
Abbexa |
10 nmol |
EUR 2000 |
Beagle dog Plasma (Non-Sterile Sodium Heparin) |
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abx800099-1L |
Abbexa |
1 L |
EUR 7910.4 |
|
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Beagle dog Plasma (Non-Sterile Sodium Heparin) |
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abx800099-5nmol |
Abbexa |
5 nmol |
EUR 1200 |
 Hepatocytes of male Wistar rat in monolayer, in 6 well-plate |
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LORIF06-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Wistar rat in monolayer, in 12 well-plate |
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LORIF12-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Wistar rat in monolayer, in 24 well-plate |
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LORIF24-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Wistar rat in monolayer, in 48 well-plate |
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LORIF48-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Wistar rat in monolayer, in 96 well-plate |
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LORIF96-EU |
Westburg |
each |
Ask for price |
 Male Cynomolgus monkey HEPATOCYTES in monolayer, in 6 well-plate |
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LOCYF06-EU |
Westburg |
each |
Ask for price |
 Male Cynomolgus monkey HEPATOCYTES in monolayer, in 12 well-plate |
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LOCYF12-EU |
Westburg |
each |
Ask for price |
 Male Cynomolgus monkey HEPATOCYTES in monolayer, in 24 well-plate |
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LOCYF24-EU |
Westburg |
each |
Ask for price |
 Male Cynomolgus monkey HEPATOCYTES in monolayer, in 48 well-plate |
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LOCYF48-EU |
Westburg |
each |
Ask for price |
 Beagle dog Serum Sterile |
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20-abx800094 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
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- Shipped within 1-5 working days.
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Beagle dog Serum Sterile |
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abx800094-10nmol |
Abbexa |
10 nmol |
EUR 2162.5 |
Beagle dog Serum Sterile |
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abx800094-1L |
Abbexa |
1 L |
EUR 9096 |
- Shipped within 1-5 working days.
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Beagle dog Serum Sterile |
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abx800094-5nmol |
Abbexa |
5 nmol |
EUR 1262.5 |
, Mouse and Rat) Liver Dissociation System 6 (Hepatocytes,Nonparenchymal), Mouse and Rat |
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4-20306 |
CHI Scientific |
ea |
EUR 195.92 |
) Beagle dog Whole Blood (Non-Sterile Sodium Heparin) |
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20-abx800105 |
Abbexa |
-
Ask for price
-
Ask for price
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- Shipped within 1-5 working days.
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Beagle dog Whole Blood (Non-Sterile Sodium Heparin) |
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abx800105-10nmol |
Abbexa |
10 nmol |
EUR 1800 |
Beagle dog Whole Blood (Non-Sterile Sodium Heparin) |
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abx800105-5nmol |
Abbexa |
5 nmol |
EUR 1000 |
 Hepatocytes of male Sprague Dawley rat in monolayer, in 6 well plate |
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LORSF06-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Sprague Dawley rat in monolayer, in 12 well plate |
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LORSF12-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Sprague Dawley rat in monolayer, in 24 well plate |
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LORSF24-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Sprague Dawley rat in monolayer, in 48 well plate |
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LORSF48-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Sprague Dawley rat in monolayer, in 96 well plate |
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LORSF96-EU |
Westburg |
each |
Ask for price |
 Hepatocytes of male Sprague Dawley rat in suspension , 10 million cells |
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LORSFS10-EU |
Westburg |
each |
Ask for price |
 Human hepatocytes in monolayer-long term cultures, in 6 well-plate |
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LOHUF06-EU |
Westburg |
each |
Ask for price |
 Human hepatocytes in monolayer-long term cultures, in 12 well-plate |
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LOHUF12-EU |
Westburg |
each |
Ask for price |
 Human hepatocytes in monolayer-long term cultures, in 24 well-plate |
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LOHUF24-EU |
Westburg |
each |
Ask for price |
 Human hepatocytes in monolayer-long term cultures, in 48 well-plate |
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LOHUF48-EU |
Westburg |
each |
Ask for price |
 Human hepatocytes in monolayer-long term cultures, in 96 well-plate |
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LOHUF96-EU |
Westburg |
each |
Ask for price |
, Mouse and Rat) Liver Dissociation System 3 (Hepatocytes, Kupffer, Parenchymal), Mouse and Rat |
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4-20303 |
CHI Scientific |
ea |
EUR 144.82 |
) Beagle dog Serum (Non-Sterile) |
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20-abx800093 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
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- Shipped within 1-5 working days.
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Beagle dog Serum (Non-Sterile) |
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abx800093-10nmol |
Abbexa |
10 nmol |
EUR 2000 |
Beagle dog Serum (Non-Sterile) |
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abx800093-1L |
Abbexa |
1 L |
EUR 7108.8 |
- Shipped within 1-5 working days.
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Beagle dog Serum (Non-Sterile) |
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abx800093-5nmol |
Abbexa |
5 nmol |
EUR 1200 |
) Beagle dog Red Blood Cells (100%) |
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20-abx800107 |
Abbexa |
-
Ask for price
-
Ask for price
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- Shipped within 1-5 working days.
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Beagle dog Red Blood Cells (100%) |
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abx800107-10nmol |
Abbexa |
10 nmol |
EUR 2300 |
Beagle dog Red Blood Cells (100%) |
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abx800107-5nmol |
Abbexa |
5 nmol |
EUR 1312.5 |
) Beagle dog Plasma (Sterile Sodium EDTA) |
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20-abx800098 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
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Beagle dog Plasma (Sterile Sodium EDTA) |
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abx800098-10nmol |
Abbexa |
10 nmol |
EUR 2162.5 |
Beagle dog Plasma (Sterile Sodium EDTA) |
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abx800098-1L |
Abbexa |
1 L |
EUR 10466.4 |
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Beagle dog Plasma (Sterile Sodium EDTA) |
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abx800098-5nmol |
Abbexa |
5 nmol |
EUR 1262.5 |
) Beagle dog Plasma (Sterile Sodium Citrate) |
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20-abx800096 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
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|
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Beagle dog Plasma (Sterile Sodium Citrate) |
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abx800096-10nmol |
Abbexa |
10 nmol |
EUR 2162.5 |
Beagle dog Plasma (Sterile Sodium Citrate) |
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abx800096-1L |
Abbexa |
1 L |
EUR 10466.4 |
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Beagle dog Plasma (Sterile Sodium Citrate) |
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abx800096-5nmol |
Abbexa |
5 nmol |
EUR 1262.5 |
) Beagle dog Whole Blood (Sterile Sodium EDTA) |
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20-abx800104 |
Abbexa |
-
Ask for price
-
Ask for price
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- Shipped within 1-5 working days.
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Beagle dog Whole Blood (Sterile Sodium EDTA) |
|
abx800104-10nmol |
Abbexa |
10 nmol |
EUR 2000 |
Beagle dog Whole Blood (Sterile Sodium EDTA) |
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abx800104-5nmol |
Abbexa |
5 nmol |
EUR 1100 |
) Beagle dog Plasma (Non-Sterile Sodium EDTA) |
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20-abx800097 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
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|
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Beagle dog Plasma (Non-Sterile Sodium EDTA) |
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abx800097-10nmol |
Abbexa |
10 nmol |
EUR 2000 |
Beagle dog Plasma (Non-Sterile Sodium EDTA) |
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abx800097-1L |
Abbexa |
1 L |
EUR 7910.4 |
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Beagle dog Plasma (Non-Sterile Sodium EDTA) |
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abx800097-5nmol |
Abbexa |
5 nmol |
EUR 1200 |
) Beagle dog Whole Blood (Sterile Sodium Citrate) |
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20-abx800102 |
Abbexa |
-
Ask for price
-
Ask for price
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- Shipped within 1-5 working days.
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Beagle dog Whole Blood (Sterile Sodium Citrate) |
|
abx800102-10nmol |
Abbexa |
10 nmol |
EUR 2000 |
Beagle dog Whole Blood (Sterile Sodium Citrate) |
|
abx800102-5nmol |
Abbexa |
5 nmol |
EUR 1100 |
) Beagle dog Plasma (Non-Sterile Sodium Citrate) |
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20-abx800095 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
|
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Beagle dog Plasma (Non-Sterile Sodium Citrate) |
|
abx800095-10nmol |
Abbexa |
10 nmol |
EUR 2000 |
Beagle dog Plasma (Non-Sterile Sodium Citrate) |
|
abx800095-1L |
Abbexa |
1 L |
EUR 7910.4 |
|
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Beagle dog Plasma (Non-Sterile Sodium Citrate) |
|
abx800095-5nmol |
Abbexa |
5 nmol |
EUR 1200 |
 Dog Hepatocyte Growth Factor ELISA kit |
|
E08H0208-192T |
BlueGene |
192 tests |
EUR 1524 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
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Description: A competitive ELISA for quantitative measurement of Canine Hepatocyte Growth Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Hepatocyte Growth Factor ELISA kit |
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E08H0208-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
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Description: A competitive ELISA for quantitative measurement of Canine Hepatocyte Growth Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Hepatocyte Growth Factor ELISA kit |
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E08H0208-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
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Description: A competitive ELISA for quantitative measurement of Canine Hepatocyte Growth Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Dog Hepatocyte growth factor ELISA Kit |
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MBS2880226-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4080 |
Dog Hepatocyte growth factor ELISA Kit |
|
MBS2880226-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 390 |
Dog Hepatocyte growth factor ELISA Kit |
|
MBS2880226-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2220 |
Dog Hepatocyte growth factor ELISA Kit |
|
MBS2880226-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 520 |
Dog Hepatocyte growth factor ELISA Kit |
|
MBS9424989-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2985 |
Dog Hepatocyte growth factor ELISA Kit |
|
MBS9424989-96Tests |
MyBiosource |
96Tests |
EUR 650 |
 Protein) Dog Hepatocyte Growth Factor (HGF) Protein |
|
abx166357-100g |
Abbexa |
100 µg |
EUR 775 |
Dog Hepatocyte Growth Factor (HGF) Protein |
|
20-abx166357 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
-
10 ug
-
50 ug
-
100 ug
-
200 ug
-
1 mg
|
- Shipped within 5-7 working days.
|
Dog Hepatocyte Growth Factor (HGF) Protein |
|
abx166357-10g |
Abbexa |
10 µg |
EUR 437.5 |
Dog Hepatocyte Growth Factor (HGF) Protein |
|
abx166357-50g |
Abbexa |
50 µg |
EUR 637.5 |
 CLIA Kit) Dog Hepatocyte Growth Factor (HGF) CLIA Kit |
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20-abx190801 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
|
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96 tests
-
5 × 96 tests
-
10 × 96 tests
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- Shipped within 5-7 working days.
|
CLIA Kit) Dog Hepatocyte Growth Factor (HGF)CLIA Kit |
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SCA047Ca-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 7719.84 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Dog Hepatocyte Growth Factor (HGF) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay: CV<12%
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Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Dog Hepatocyte Growth Factor (HGF) in serum, plasma and other biological fluids. |
Dog Hepatocyte Growth Factor (HGF)CLIA Kit |
|
SCA047Ca-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 740.93 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Dog Hepatocyte Growth Factor (HGF) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay: CV<12%
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Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Dog Hepatocyte Growth Factor (HGF) in serum, plasma and other biological fluids. |
Dog Hepatocyte Growth Factor (HGF)CLIA Kit |
|
SCA047Ca-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 1007.04 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Dog Hepatocyte Growth Factor (HGF) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay: CV<12%
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Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Dog Hepatocyte Growth Factor (HGF) in serum, plasma and other biological fluids. |
Dog Hepatocyte Growth Factor (HGF)CLIA Kit |
|
SCA047Ca-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 4171.68 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Dog Hepatocyte Growth Factor (HGF) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay: CV<12%
|
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Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Dog Hepatocyte Growth Factor (HGF) in serum, plasma and other biological fluids. |
Dog Hepatocyte Growth Factor (HGF) CLIA Kit |
|
4-SCA047Ca |
Cloud-Clone |
-
Ask for price
-
Ask for price
-
Ask for price
|
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1 plate of 96 wells
-
5 plates of 96 wells
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10 plates of 96 wells
|
- Known also as Hepatocyte Growth Factor Clia kit. Alternative names of the recognized antigen: HGF
- F-TCF
- HGFB
- HPTA
- SF
- Scatter Factor
- Hepapoietin A
- Fibroblast-Derived Tumor Cytotoxic Factor
- Lung Fibroblast-Derived Mitogen
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Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Dog Hepatocyte Growth Factor (HGF)Serum, plasma and other biological fluids |
Particularly, main rat hepatocytes had been cocultured with NIH-3T3 fibroblasts on mushy (2 kPa) and stiff substrates that recreates physiologic (2 kPa) and cirrhotic liver stiffness (55 kPa). Urea synthesis by main hepatocytes trusted the presence of fibroblast and was unbiased of the substrate stiffness. Nevertheless, albumin synthesis and Cytochrome P450 enzyme exercise elevated in hepatocytes on mushy substrates and when in coculture with a fibroblast. Western blot evaluation of hepatic markers, E-cadherin, confirmed that hepatocytes on mushy substrates in coculture promoted higher upkeep of the hepatic phenotype. These findings point out the position of stiffness in regulating the hepatocytes interactions with NPCs mandatory for upkeep of hepatocytes perform.
