Iron is important for erythropoiesis and different organic processes, however is poisonous in extra. Dietary absorption of iron is a extremely regulated course of and is a serious determinant of physique iron ranges. Iron excretion, nonetheless, is taken into account a passive, unregulated course of, and the underlying pathways are unknown. Right here we investigated the function of metallic transporters SLC39A14 and SLC30A10 in biliary iron excretion.
Whereas SLC39A14 imports manganese into the liver and different organs beneath physiological circumstances, it imports iron beneath circumstances of iron extra. SLC30A10 exports manganese from hepatocytes into the bile. We hypothesized that biliary excretion of extra iron could be impaired by SLC39A14 and SLC30A10 deficiency.
We due to this fact analyzed biliary iron excretion in Slc39a14- and Slc30a10-deficient mice raised on iron-sufficient and -rich diets. Bile was collected surgically from mice then analyzed with non-heme iron assays, mass spectrometry, ELISAs, and an electrophoretic assay for iron-loaded ferritin. Our outcomes help a mannequin during which biliary excretion of extra iron requires iron import into hepatocytes by SLC39A14, adopted by iron export into bile predominantly as ferritin, with iron export occurring independently of SLC30A10. To our information, that is the primary report of a molecular determinant of mammalian iron excretion, and may function foundation for future investigations into mechanisms of iron excretion and relevance to iron homeostasis.
Rat Cholesterol ELISA ELISA |
E01A11128 |
Goat Cholesterol ELISA ELISA |
E01A46041 |
Mouse Cholesterol ELISA ELISA |
E01A19869 |
Extracellular vesicles activate ATM-Chk2 signaling pathway by the intercellular switch of mitochondrial DNA in HBV-infected human hepatocytes
Hepatitis B virus (HBV) is a human hepatotropic pathogen inflicting hepatocellular carcinoma. We not too long ago obtained HBV-susceptible immortalized human hepatocyte NKNT-Three by exogenously expressing NTCP and its derived cell clones, #28.3.eight and #28.3.25.13 exhibiting totally different ranges of HBV susceptibility.
Within the current research, we confirmed that HBV an infection activated the ATM-Chk2 signaling pathway in #28.3.25.13 cells however not in #28.3.eight cells. Each the cell tradition supernatant and extracellular vesicles (EVs) derived from HBV-infected #28.3.25.13 cells additionally activated the ATM-Chk2 signaling pathway in naïve #28.3.25.13 cells.
Curiously, EVs derived from HBV-infected #28.3.25.13 cells included increased stage of mitochondrial DNA (mtDNA) than these from HBV-infected #28.3.eight cells. Primarily based on our outcomes, we suggest the novel mannequin that EVs mediate the activation of ATM-Chk2 signaling pathway by the intercellular switch of mtDNA in HBV-infected human hepatocyte.
Results of Iron Oxide Nanoparticles on Structural Group of Hepatocyte Chromatin: Grey Stage Co-occurrence Matrix Evaluation
Grey stage co-occurrence matrix (GLCM) evaluation is a up to date and progressive computer-based algorithm that can be utilized for the quantification of refined modifications in a mobile construction. On this work, we use this methodology for the detection of discrete alterations in hepatocyte chromatin distribution after in vivo publicity to iron oxide nanoparticles (IONPs). The research was carried out on 40 male, wholesome C57BL/6 mice divided into 4 teams: three experimental teams that acquired totally different doses of IONPs and 1 management group.
We describe the dose-dependent discount of chromatin textural uniformity measured as GLCM angular second second. Related modifications have been detected for chromatin textural uniformity expressed as the worth of inverse distinction second. To the perfect of our information, that is the primary research to research the affect of iron-based nanomaterials on hepatocyte GLCM parameters.
Additionally, that is the primary research to use discrete wavelet rework evaluation, as a supplementary methodology to GLCM, for the evaluation of hepatocyte chromatin construction in these circumstances. The outcomes could current the helpful foundation for future analysis on the applying of GLCM and DWT strategies in pathology and different medical analysis areas.
Selective Imaging of HClO within the Liver Tissue in vivo Utilizing a Close to-infrared Hepatocyte-specific Fluorescent Probe
Liver damage is typified by an inflammatory response. Hypochlorous acid (HClO), an vital endogenous reactive oxygen species, is considered a biomarker related to liver damage. Close to-infrared (NIR) fluorescent probes with the benefit of deep tissue penetrating and low auto-fluorescence interference are extra appropriate for bioimaging in vivo . Thus, on this work, we designed and synthesized a novel NIR hepatocyte-specific fluorescent probe named NHF .
The probe NHF confirmed quick response (< 3s), massive spectral variation, and good selectivity to hint HClO in buffer answer. By using N -acetylgalactosamine (
parafina) because the concentrating on ligand, probe NHF could be actively delivered to the liver tissue of zebrafish and mice. It’s important that probe NHF is the primary NIR hepatocyte-specific fluorescent probe, which efficiently visualized the up-regulation of endogenous HClO within the oxygen-glucose deprivation/reperfusion (OGD/R) mannequin HepG2 cells and dynamically monitored APAP-induced endogenous HClO within the liver tissue of zebrafish and mice.
Potential protecting impact of hesperidin on hypoxia/reoxygenation-induced hepatocyte damage
Hesperidin (HDN) has been reported to have hydrogen radical- and hydrogen peroxide-removal actions and to serve an antioxidant function in organic techniques. Nonetheless, whether or not HDN protects hepatocytes (HCs) towards hypoxia/reoxygenation (H/R)-induced damage stays unknown. The current research aimed to discover the function of HDN in H/R-induced damage. HCs have been remoted and cultured beneath H/R circumstances with or with out HDN therapy.
HC harm was markedly induced beneath H/R, as indicated by cell viability, supernatant lactate dehydrogenase ranges and alanine aminotransferase ranges; nonetheless, HDN therapy considerably reversed HC damage. Oxidative stress markers (malondialdehyde, superoxide dismutase, glutathioneand reactive oxygen species) have been elevated markedly throughout H/R in HCs; nonetheless, this impact was considerably attenuated after publicity to HDN. In contrast with these of the management group, the mRNA expression ranges of IL-6 and TNF-α in HCs and the concentrations of IL-6 and TNF-α within the supernatants elevated considerably following H/R, and HDN considerably ameliorated these results.
Primary Human Hepatocytes, Transporter Uptake Qualified |
T0125 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 3500 |
Enhanced Primary Human Hepatocytes – 1 Million |
T5995 |
ABM |
1x10^6 cells / 1.0ml |
Ask for price |
Primary Human Hepatocytes, Induction Qualified, Plateable |
T0128 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 2625 |
Primary Human Hepatocytes, Metabolism Qualified, Plateable |
T0124 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 2625 |
Primary Human Hepatocytes, Metabolism Qualified, Suspension |
T0123 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Dog (Beagle) Hepatocytes, Plateable |
T0118 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Dog (Beagle) Hepatocytes, Suspension |
T0117 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Rat (Fischer) Hepatocytes, Plateable |
T0108 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Rat (Fischer) Hepatocytes, Suspension |
T0107 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Mouse (CD-1) Hepatocytes, Plateable |
T0120 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Mouse (CD-1) Hepatocytes, Suspension |
T0119 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Monkey (Cynomolgus) hepatocytes, Plateable |
T0112 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Mouse (C57BI/6) Hepatocytes, Plateable |
T0122 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Rat (Wistar Han) Hepatocytes, Plateable |
T0106 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Minipig (Gottingen) Hepatocytes, Suspension |
T0113 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Monkey (Cynomolgus) Hepatocytes, Suspension |
T0111 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Mouse (C57BI/6) Hepatocytes, Suspension |
T0121 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Rat (Wistar Han) Hepatocytes, Suspension |
T0105 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Rat (Sprague Dawley) Hepatocytes, Plateable |
T0104 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Rat (Sprague Dawley) Hepatocytes, Suspension |
T0103 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Primary Rabbit (New Zealand White) Hepatocytes, Suspension |
T0115 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 1375 |
Human Liver PrimaCell: Hepatocytes |
2-96121 |
CHI Scientific |
1 Kit |
Ask for price |
Rat Liver PrimaCell: Hepatocytes |
2-82595 |
CHI Scientific |
1 Kit |
Ask for price |
Human Liver PrimaCell: Normal Hepatocytes Growth Medium |
9-46121 |
CHI Scientific |
5 x 100 ml |
Ask for price |
Mouse Liver PrimaCell: Hepatocytes |
2-82100 |
CHI Scientific |
1 Kit |
Ask for price |
Human Hepatocytes |
ABC-TC3646 |
AcceGen |
1 vial |
Ask for price |
|
Description: The liver fulfills many vital processes in mammals. It is the central organ of energy metabolism, biotransformation of xenobiotics, and synthesis of plasma proteins under physiological and pathophysiological conditions. Primary human hepatocyte culture is an important experimental model for the study of liver specific function. Propagation of human hepatocytes is critical for gene therapy, cell transplantation and clinical liver support systems. In appropriate culture condition, cultured human hepatocytes proliferate and maintain differentiated hepatocyte function such as the synthesis of serum proteins. HH from Gentaur Research Laboratories are isolated from human liver. HH are cryopreserved immediately after purification and delivered frozen. Each vial contains 1 x 10^6 cells in 1 ml volume. HH are characterized by immunofluorescent method with antibodies to albumin, cytokeratin-18 and vimentin. HH are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HH is not recommended for expanding or long term cultures since the cells do not proliferate in culture. |
Human Hepatocytes |
HC4230 |
Neuromics |
500,000 Cells |
EUR 991.2 |
Immortalized human hepatocytes |
ABI-TC3500 |
AcceGen |
1 vial |
Ask for price |
Description: The cell line was prepared by immortalizing hepatocytes from a 12 year-old Caucasian female donor with the SV40 large T antigen. The donor tested negative for CMV, HIV, HBV, and HCV. |
Rat Liver PrimaCell: Normal Hepatocytes Growth Medium |
9-25095 |
CHI Scientific |
5 x 100 ml |
Ask for price |
Mouse Liver PrimaCell: Normal Hepatocytes Growth Medium |
9-32100 |
CHI Scientific |
5 x 100 ml |
Ask for price |
Human Hepatocytes - Opioid Addicted |
HC4230OP |
Neuromics |
500000 |
EUR 1148.4 |
Human Hepatocytes - Opioid Addicted |
HC4230OP-B |
Neuromics |
each |
EUR 805.5 |
Human Hepatocytes - Alcohol Addicted |
HC4230AA |
Neuromics |
500,000 Cells |
EUR 1148.4 |
Human Hepatocytes - Alcohol Addicted |
HC4230AA-B |
Neuromics |
each |
EUR 625.5 |
Immortalized Human Hepatocytes - Ras |
T0059 |
ABM |
1x106 cells / 1.0 ml |
Ask for price |
Human iPSC-derived Hepatocytes |
CSC-00863L |
Creative Bioarray |
One Frozen vial |
Ask for price |
|
Human Liver PrimaCell: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium) |
9-47121 |
CHI Scientific |
1 Set |
Ask for price |
Immortalized Human Hepatocytes - hTERT |
T0058 |
ABM |
1x106 cells / 1.0 ml |
Ask for price |
Immortalize Human Hepatocytes-SV40 |
CSC-I9016L |
Creative Bioarray |
One Frozen vial |
Ask for price |
Human Fresh Hepatocytes, Suspension |
ABC-TC3432 |
AcceGen |
1 vial |
Ask for price |
|
Description: Freshly isolated human hepatocytes represent a living biological system in which to measure metabolism, induction, toxicity, and transporter studies. |
Human Pooled Hepatocytes(Heps 10) |
ABC-TC3458 |
AcceGen |
1 vial |
Ask for price |
|
Description: Human Pooled Primary Hepatocytes (Heps) provide an ideal culture model for drug testing and drug development.Heps 20 Human Pooled Primary Hepatocytes contain cryopreserved hepatocytes pooled from 20 different donors and have undergone only one freeze cycle. Pooled hepatocytes provide the genetic diversity necessary for superior reliability and predictability of the metabolic characteristics of a test compound relative to a representative population. Pooled hepatocytes increase experimental control and reduce costs by eliminating the need to conduct redundant experiments necessary to obtain population-based data. Each lot has undergone a single freeze cycle, assuring maximum hepatocyte viability and consistency from donor to donor within the pool.Cell Features:Each donor's hepatocytes have been cryopreserved ONCE immediately after isolation and purification.Pools of 10 or 20 donors are available. Each donor is represented by a statistically significant number of cells relative to the pool.There is extensive quality control providing characterization of viability and enzyme activity from both individual donors and the total pool.Gentaur guarantees performance and quality.Donor information is available. |
Human Pooled Hepatocytes(Heps 20) |
ABC-TC3459 |
AcceGen |
1 vial |
Ask for price |
|
Description: Human Pooled Primary Hepatocytes (HP2 Heps) provide an ideal culture model for drug testing and drug development. HP2 10 Human Pooled Primary Hepatocytes contain cryopreserved hepatocytes pooled from 10 different donors and have undergone only one freeze cycle. Pooled hepatocytes provide the genetic diversity necessary for superior reliability and predictability of the metabolic characteristics of a test compound relative to a representative population. Pooled hepatocytes increase experimental control and reduce costs by eliminating the need to conduct redundant experiments necessary to obtain population-based data. Each lot has undergone a single freeze cycle, assuring maximum hepatocyte viability and consistency from donor to donor within the pool.Cell Features:Each donor's hepatocytes have been cryopreserved ONCE immediately after isolation and purification.Pools of 10 or 20 donors are available. Each donor is represented by a statistically significant number of cells relative to the pool.There is extensive quality control providing characterization of viability and enzyme activity from both individual donors and the total pool.Gentaur guarantees performance and quality.Donor information is available. |
Human Hepatocytes-Single Donor, Male |
ABC-TC3649 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur's hepatocytes for suspension assays (HP1 Heps-s - single donor, male) provide an economic source of characterized human hepatocytes for use in short-term suspension assays to evaluate the metabolism of drug candidates. Gentaur's hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
Human Hepatocytes-Single Donor, Female |
ABC-TC3647 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur's hepatocytes for suspension assays (HP1 Heps-s, single donor, female) provide an economic source of characterized human hepatocytes for use in short-term suspension assays to evaluate the metabolism of drug candidates. Gentaur's hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
Rat Hepatocytes |
ABC-TC4136 |
AcceGen |
1 vial |
Ask for price |
|
Description: Rat Hepatocytes (RH) are isolated from adult rat livers. They are cryopreserved at the end of primary cell isolation. |
Mouse Hepatocytes |
ABC-TC3928 |
AcceGen |
1 vial |
Ask for price |
|
Description: Our High Quality Mouse Hepatocytes have been isolated from mouse livers after liver perfusion and low-speed differential centrifugation. The hepatocytes are cryoperserved immediately after the experimental process and delivered frozen. |
Bovine Hepatocytes |
ABC-TC3132 |
AcceGen |
1 vial |
Ask for price |
|
Description: Bovine hepatocytes, 4-week bovine |
Human Mature Hepatocytes, Non-Plateable |
ABC-TC3893 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
MCHT50 - Cryo Human Hepatocytes thawing media |
LOMCHT50 |
Westburg |
each |
EUR 102.95 |
HighQC™ Human IPSC-Derived Hepatocytes |
ABC-SC2119 |
AcceGen |
1 vial |
Ask for price |
Description: These hepatocytes overcome the functionality, reproducibility, and availability limitations of existing primary cell and tumor-derived cell models by providing the following:Relevant hepatic functionality and phenotypic stabilityExpression of clinical targets that are relevant for liver and metabolic diseaseCompatibility with a wide range of 3D and microphysiological systemsQuality-controlled manufacturing and batch reproducibilityReady supply in a cryopreserved format |
Human Hepatocytes-Single Donor, Male; Inducible |
ABC-TC3650 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur's inducible hepatocytes (HP1 Heps-i, single donor, male) can be plated and used in long-term drug induction studies or metabolic studies where long-term incubations are required. Gentaur's cryopreserved primary human hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is tested for plating and provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
Human Plateable Hepatocytes From Whole Livers |
ABC-TC4022 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
Human Hepatocytes-Single Donor, Female; Inducible |
ABC-TC3648 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur's inducible hepatocytes (HP1 Heps-i, single donor, female) can be plated and used in long-term drug induction studies or metabolic studies where long-term incubations are required. Gentaur's cryopreserved primary human hepatocytes are a functional, convenient and economical solution for your drug testing and basic research needs. Each lot is tested for plating and provided with extensive characterization of metabolic functionality to ensure that you receive an ideal model for drug testing, drug development or other metabolic studies. Gentaur's human hepatocytes eliminate the need and expense of obtaining liver tissue, and conducting multiple cell isolations; and Gentaur also provides hepatocyte-tested culture reagents and instructions necessary for thawing and culturing your hepatocytes.Cell Features:Suitable for induction assays or metabolic characterization assays in plated or suspension cultures. Plated cultures are excellent for long-term intrinsic clearance assays.Hepatocytes are cryopreserved ONCE immediately after isolation and purification.Characterization of viability and enzyme activity, including fold-induction of CYP1A2, CYP2B6 and CYP3A4 for HP1 Heps-i.Gentaur guarantees performance and quality.Donor demographics and medical information are available. |
Liver Dissociation System 2 (Hepatocytes, Parenchymal hepatocytes), Mouse and Rat |
4-20302 |
CHI Scientific |
ea |
Ask for price |
Immortalized Human Hepatocytes - HPVE6/E7 and Myc |
T0057 |
ABM |
1x10^6 cells / 1.0 ml |
EUR 350 |
Rabbit Liver Hepatocytes |
ABC-TC4061 |
AcceGen |
1 vial |
Ask for price |
|
Description: Rabbit liver epithelial cells, 5-week rabbit |
Human hepatocytes in suspension , 10 million cells |
LOHUFS10-EU |
Westburg |
each |
Ask for price |
Rat Plateable Hepatocytes |
ABC-TC4024 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
Plateable Mouse Hepatocytes |
ABC-TC4023 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
Rat Liver PrimaCell: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium) |
9-26095 |
CHI Scientific |
1 Set |
Ask for price |
Mouse Liver PrimaCell: Normal Hepatocytes Growth Supplements with Serum (for 500 ml medium) |
9-33100 |
CHI Scientific |
1 Set |
Ask for price |
Immortalized Monkey Hepatocytes |
CSC-I2072Z |
Creative Bioarray |
One Frozen vial |
Ask for price |
Immortalized Human Hepatocytes - HPV E6/E7, hTERT & MycT58A |
T0063 |
ABM |
1x10^6 cells / 1.0 ml |
EUR 350 |
Human Liver Tissue Preparation Buffer: Normal Hepatocytes |
9-80314 |
CHI Scientific |
1 x 100 ml |
Ask for price |
Plateable DOG (Beagle) Hepatocytes |
ABC-TC4021 |
AcceGen |
1 vial |
Ask for price |
|
Description: Gentaur offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and suspension cells are available. Custom configurations are available upon request. |
Immortalized Rat Hepatocytes - SV40 |
T0078 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
Rat Hepatocytes Suspension-Adult |
ABC-TC4137 |
AcceGen |
1 vial |
Ask for price |
|
Description: Rat Hepatocytes Suspension - Adult |
Immortalized Mouse Hepatocytes - SV40 |
T0101 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
Immortalized Hamster Hepatocytes (SV40) |
T0072 |
ABM |
1x10^6 cells / 1.0 ml |
Ask for price |
Immortalized Mouse Hepatocytes-SV40 |
CSC-I2205Z |
Creative Bioarray |
One Frozen vial |
Ask for price |
Immortalized Monkey Hepatocytes-SV40 |
T0073 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
Cryo Dog (Beagle) Hepatocytes, Plateable |
LODBCP01 |
Westburg |
each |
EUR 1002.34 |
Cryo Rat (Wistar) Hepatocytes, Plateable |
LORICP01 |
Westburg |
each |
EUR 552.24 |
Cryo Monkey (Cyno) Hepatocytes, Plateable |
LOCYCP01 |
Westburg |
each |
EUR 965.52 |
Cryo Dog (Beagle) Hepatocytes, Suspension |
LODBCS01 |
Westburg |
each |
EUR 390.63 |
Cryo Rat (Wistar) Hepatocytes, Suspension |
LORICS01 |
Westburg |
each |
EUR 328.97 |
Cryo Monkey (Cyno) Hepatocytes, Suspension |
LOCYCS01 |
Westburg |
each |
EUR 517.8 |
HighQC™ Mouse Hepatocytes Stem Cell |
ABC-SC0041 |
AcceGen |
1 vial |
Ask for price |
Description: Mouse Hepatocyte Stem Cells; Frozen Vial and Plated cells are available. Cells are only guaranteed with purchase of Gentaur Media and Gentaur Extra Cellular Matrix for appropriate cell culture, for 30 days from the date of shipment. |
Cryo Mouse (CD-1) Hepatocytes, Pltable |
LOMCCP01 |
Westburg |
each |
EUR 1102.09 |
Cryo Monkey (Rhesus) Hepatocytes, Plateable |
LORHCP01 |
Westburg |
each |
EUR 965.52 |
Cryo monkey (Rhesus) Hepatocytes, Suspension |
LORHCS01 |
Westburg |
each |
EUR 517.8 |
Immortalized Sprague Dawley Rats Hepatocytes |
ABI-TC047D |
AcceGen |
1 vial |
Ask for price |
Description: Sprague Dawley rats hepatocytes conditionally Immortalised with temperature sensitive SV40 large T antigen. |
Human hepatocytes in monolayer-long term cultures, in 6 well-plate |
LOHUF06-EU |
Westburg |
each |
Ask for price |
Human hepatocytes in monolayer-long term cultures, in 12 well-plate |
LOHUF12-EU |
Westburg |
each |
Ask for price |
Human hepatocytes in monolayer-long term cultures, in 24 well-plate |
LOHUF24-EU |
Westburg |
each |
Ask for price |
Human hepatocytes in monolayer-long term cultures, in 48 well-plate |
LOHUF48-EU |
Westburg |
each |
Ask for price |
Human hepatocytes in monolayer-long term cultures, in 96 well-plate |
LOHUF96-EU |
Westburg |
each |
Ask for price |
Immortalized Monkey Hepatocytes-SV40 T+t |
T0074 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
C57BL/6 Mouse Hepatocytes Suspension-Adult |
ABC-TC3192 |
AcceGen |
1 vial |
Ask for price |
|
Description: C57BL/6 Mouse Hepatocytes Suspension - Adult |
Cryo Rat (Sprague Dawley) Hepatocytes, Plateable |
LORSCP01 |
Westburg |
each |
EUR 552.24 |
Immortalized Hamster Hepatocytes-SV40 T+t |
T0071 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
Liver Dissociation System 1 (Hepatocytes), Mouse |
4-20301 |
CHI Scientific |
ea |
Ask for price |
Cryo Rat (Sprague Dawley) Hepatocytes, Suspension |
LORSCS01 |
Westburg |
each |
EUR 328.97 |
Cryo Rat (Wistar Hannover) Hepatocytes, Plateable |
LORWCP01 |
Westburg |
each |
EUR 552.24 |
Male Beagle dog HEPATOCYTES , 10 million cells |
LODBFS10-EU |
Westburg |
each |
Ask for price |
Wistar male rat HEPATOCYTES , 10 million cells |
LORIFS10-EU |
Westburg |
each |
Ask for price |
Conditionally Immortalized Rat Hepatocytes-SV40T |
CSC-I2094Z |
Creative Bioarray |
One Frozen vial |
Ask for price |
Cryo Rat (Wistar Hannover) Hepatocytes, Suspension |
LORWCS01 |
Westburg |
each |
EUR 328.97 |
Immortalized Mouse Hepatocytes-Conditionally (ImHep) |
T0099 |
ABM |
1x106 cells / 1.0 ml |
EUR 3950 |
Liver Dissociation System 4 (Hepatocytes, rat), Rat |
4-20304 |
CHI Scientific |
ea |
Ask for price |
Male Cynomolgus monkey HEPATOCYTES , 10 million cells |
LOCYFS10-EU |
Westburg |
each |
Ask for price |
Rat Liver Tissue Preparation Buffer: Normal Hepatocytes |
9-80322 |
CHI Scientific |
1 x 100 ml |
Ask for price |
Mouse Liver Tissue Preparation Buffer: Normal Hepatocytes |
9-80306 |
CHI Scientific |
1 x 100 ml |
Ask for price |
Hepatocytes of male Beagle dog in monolayer, in 6 well-plate |
LODBF06-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Beagle dog in monolayer, in 12 well-plate |
LODBF12-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Beagle dog in monolayer, in 24 well-plate |
LODBF24-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Beagle dog in monolayer, in 48 well-plate |
LODBF48-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Beagle dog in monolayer, in 96 well-plate |
LODBF96-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Wistar rat in monolayer, in 6 well-plate |
LORIF06-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Wistar rat in monolayer, in 12 well-plate |
LORIF12-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Wistar rat in monolayer, in 24 well-plate |
LORIF24-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Wistar rat in monolayer, in 48 well-plate |
LORIF48-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Wistar rat in monolayer, in 96 well-plate |
LORIF96-EU |
Westburg |
each |
Ask for price |
Male Cynomolgus monkey HEPATOCYTES in monolayer, in 6 well-plate |
LOCYF06-EU |
Westburg |
each |
Ask for price |
Male Cynomolgus monkey HEPATOCYTES in monolayer, in 12 well-plate |
LOCYF12-EU |
Westburg |
each |
Ask for price |
Male Cynomolgus monkey HEPATOCYTES in monolayer, in 24 well-plate |
LOCYF24-EU |
Westburg |
each |
Ask for price |
Male Cynomolgus monkey HEPATOCYTES in monolayer, in 48 well-plate |
LOCYF48-EU |
Westburg |
each |
Ask for price |
Liver Dissociation System 6 (Hepatocytes,Nonparenchymal), Mouse and Rat |
4-20306 |
CHI Scientific |
ea |
Ask for price |
Hepatocytes of male Sprague Dawley rat in monolayer, in 6 well plate |
LORSF06-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Sprague Dawley rat in monolayer, in 12 well plate |
LORSF12-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Sprague Dawley rat in monolayer, in 24 well plate |
LORSF24-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Sprague Dawley rat in monolayer, in 48 well plate |
LORSF48-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Sprague Dawley rat in monolayer, in 96 well plate |
LORSF96-EU |
Westburg |
each |
Ask for price |
Hepatocytes of male Sprague Dawley rat in suspension , 10 million cells |
LORSFS10-EU |
Westburg |
each |
Ask for price |
Liver Dissociation System 3 (Hepatocytes, Kupffer, Parenchymal), Mouse and Rat |
4-20303 |
CHI Scientific |
ea |
Ask for price |
Human Primary hepatic carcinoma ELISA kit |
E01A7068 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Human Primary hepatic carcinoma ELISA kit |
E01P0656-192T |
BlueGene |
192 tests |
EUR 1524 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Human Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Primary hepatic carcinoma ELISA kit |
E01P0656-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Human Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Primary hepatic carcinoma ELISA kit |
E01P0656-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Human Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Primary hepatic carcinoma ELISA Kit |
MBS726869-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Human Primary hepatic carcinoma ELISA Kit |
MBS726869-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Human Primary hepatic carcinoma ELISA Kit |
MBS726869-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Human Primary hepatic carcinoma ELISA Kit |
MBS726869-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Normal Human Primary Hepatic Kupffer Cells |
T5549 |
ABM |
1x10^6 cells / 1.0 ml |
EUR 1115 |
Normal Human Primary Hepatic Stellate Cells |
T5546 |
ABM |
1x10^6 cells / 1.0 ml |
EUR 1175 |
Human Primary Hepatic Non-Parenchymal Cells |
T4061 |
ABM |
5x10^5 cells / 1.0 ml |
Ask for price |
Human primary hepatic carcinoma,PHC ELISA Kit |
YLA2711HU-48T |
Shanghai YL Biotech |
48T |
Ask for price |
Human primary hepatic carcinoma,PHC ELISA Kit |
YLA2711HU-96T |
Shanghai YL Biotech |
96T |
Ask for price |
Human primary hepatic carcinoma(PHC)ELISA Kit |
GA-E1689HM-48Tests |
GenAsia Biotech |
48 Tests |
Ask for price |
Human primary hepatic carcinoma(PHC)ELISA Kit |
GA-E1689HM-96Tests |
GenAsia Biotech |
96 Tests |
EUR 388 |
Human primary hepatic carcinoma(PHC)ELISA Kit |
GA-E1689HM-48T |
GenAsia Biotech |
48T |
EUR 346.8 |
Human primary hepatic carcinoma(PHC)ELISA Kit |
GA-E1689HM-96T |
GenAsia Biotech |
96T |
EUR 559.2 |
Human primary hepatic carcinoma,PHC ELISA Kit |
SL1444Hu |
Sunlong |
96 Tests |
EUR 468 |
|
Human primary hepatic carcinoma (PHC) ELISA Kit |
MBS2613515-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3040 |
Human primary hepatic carcinoma (PHC) ELISA Kit |
MBS2613515-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 285 |
Human primary hepatic carcinoma (PHC) ELISA Kit |
MBS2613515-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1670 |
Human primary hepatic carcinoma (PHC) ELISA Kit |
MBS2613515-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 405 |
Human primary hepatic carcinoma(PHC) ELISA Kit |
EIA07811h |
Enlibio |
each |
EUR 430 |
Human primary hepatic carcinoma,PHC ELISA Kit |
201-12-1673 |
Shanghai Sunred Biological Technology |
96 tests |
EUR 528 |
- This primary hepatic carcinoma ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Primary Hepatic Sinusoidal Endothelial Cells |
T4220 |
ABM |
5x10^5 cells / 1.0 ml |
EUR 975 |
Primary Rat Hepatic Stellate Cells (HSC) |
CSI071Ra01 |
Cloud-Clone |
5X10^5 |
EUR 880 |
|
Rat Primary hepatic carcinoma ELISA kit |
E02P0656-192T |
BlueGene |
192 tests |
EUR 1524 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Rat Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Primary hepatic carcinoma ELISA kit |
E02P0656-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Rat Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Primary hepatic carcinoma ELISA kit |
E02P0656-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Rat Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Primary hepatic carcinoma ELISA kit |
E07P0656-192T |
BlueGene |
192 tests |
EUR 1524 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Porcine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Primary hepatic carcinoma ELISA kit |
E07P0656-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Porcine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Primary hepatic carcinoma ELISA kit |
E07P0656-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Porcine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Primary hepatic carcinoma ELISA kit |
E08P0656-192T |
BlueGene |
192 tests |
EUR 1524 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Canine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Primary hepatic carcinoma ELISA kit |
E08P0656-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Canine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Primary hepatic carcinoma ELISA kit |
E08P0656-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
Description: A competitive ELISA for quantitative measurement of Canine Primary hepatic carcinoma in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Primary hepatic carcinoma ELISA kit |
E01A15814 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Rat Primary hepatic carcinoma ELISA Kit |
MBS731505-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Rat Primary hepatic carcinoma ELISA Kit |
MBS731505-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Western blotting demonstrated that microtubule-associated protein 1 gentle chain 3α (MAP1LC3A, also called LC3) and Beclin-1 protein expression ranges elevated, whereas sequestosome 1 ranges decreased throughout H/R following publicity to HDN. The variety of GFP-LC3 puncta in HCs following publicity to HDN was elevated in contrast with that noticed in HCs with out HDN publicity beneath the H/R circumstances after bafilomycin A1 therapy. In abstract, the current research demonstrated that HDN attenuated HC oxidative stress and inflammatory responses whereas enhancing autophagy throughout H/R. HDN could have a possible protecting impact on HCs throughout H/R-induced damage.
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